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GlossaryTacrolimus (Topical Tacrolimus)

immunosuppressive drug used to treat eczema and prevent organ rejection

Tacrolimus is an immunosuppressive medication commonly used to prevent organ transplant rejection and to treat certain skin conditions like eczema and psoriasis. It works by inhibiting the activity of T-cells, which are part of the immune system, thereby reducing inflammation and immune responses. In dermatology, it is often available as a topical ointment under the brand name Protopic.

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community Is there any new drug that looks promising ?

in Research/Science 25 upvotes 8 months ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community PYRILUTAMIDE KX-826 experience

in Research/Science 95 upvotes 2 years ago

A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Help! Minoxidil or Duta to avoid Shed of long hair.

in Female 6 upvotes 1 month ago

The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

community Topical Dutasteride is Here.

in Finasteride/Dutasteride 153 upvotes 3 years ago

The availability of Topical Dutasteride, a potential treatment for hair loss, which can be purchased without prescription from MinoxidilMax. Other treatments discussed include Topical Finasteride and PRP injections, with discussion around dosage, efficacy, side-effects and safety.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 1 year ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Just find a cure already, I am totally done

in Chat 161 upvotes 2 months ago

The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.

community Breaking hair loss news! GT20029 is a resounding success!

in Product 138 upvotes 7 months ago

GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 1 year ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

community Why not use hair system instead of Topical Hassle

in Hair Systems 20 upvotes 4 days ago

Topical treatments like minoxidil and finasteride are preferred for hair loss due to ease of use and natural appearance. Hair systems are considered high-maintenance and less genuine.

community Why isnt topical fin talked about more?

in Chat 43 upvotes 1 week ago

Topical finasteride is less popular due to inconvenience, cost, and availability, while oral finasteride is favored for ease and safety. Some users experience side effects with topical use, but find it effective with minoxidil, though opinions on its efficacy vary.

community Topical Minoxidil Hyperresponder

in Minoxidil 9 upvotes 3 weeks ago

Minoxidil helped regrow hair from NW3 to NW2 in 5 months despite initial shedding, with additional use of Vitamin D3/K2 on the scalp. Users discuss patience during shedding and the importance of continuing treatments like Minoxidil and Finasteride.

community Topical dutasteride valid success stories

in Finasteride/Dutasteride 1 upvotes 1 month ago

Topical dutasteride may not significantly reduce hair loss and could potentially increase testosterone, leading to further hair loss. Users report side effects like mood changes, sleep issues, and severe side effects, with no significant progress in hair regrowth.

community Topical Anti-Androgen users. What are y’all using currently? And what do you believe has the best chance of being approved? Or best results?

in Technology 13 upvotes 1 month ago

RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.

community Topical Exosomes w derma roller??

in Research/Science 1 upvotes 1 month ago

The conversation discusses using topical exosomes with a derma roller for hair loss. Users also mention minoxidil for treatment.

community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?

in Chat 20 upvotes 1 month ago

Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.

community Topical min users, how long does your evening routine take?

in Chat 8 upvotes 2 months ago

Applying Minoxidil takes users between 10 seconds to 20 minutes, with most finding quicker methods more efficient. Techniques vary from using foam, liquid, or spray, with some users recommending buzz cuts for easier application.

community Topical Dutasteride & Microneedling Works

in Finasteride/Dutasteride 5 upvotes 2 months ago

Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

community Topical bicalutamide vs ru58841

in Female 1 upvotes 2 months ago

A user is seeking advice on making a topical bicalutamide solution as an alternative to RU58841 for hair loss, while already using dutasteride and minoxidil. They are considering crushing bicalutamide pills and adding them to their minoxidil.

community Has anyone used topical estrogen or estradiol for hair loss and how effective was it?

in Treatment 1 upvotes 2 months ago

Topical estrogen or estradiol for hair loss is being discussed for its effectiveness compared to finasteride. Users are sharing their experiences and opinions on its potential benefits.

community Topical Minoxidil foam + Finasteride

in Finasteride/Dutasteride 1 upvotes 2 months ago

The conversation discusses using minoxidil foam as a solvent for topical finasteride. Ingredients of minoxidil foam include butane, cetyl alcohol, glycerin, and purified water.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

in Finasteride/Dutasteride 26 upvotes 3 months ago

The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 372 upvotes 3 months ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community Topical minoxidil and salicylic acid

in Minoxidil 4 upvotes 3 months ago

The user has been using finasteride for 6 months with decent results and recently added topical minoxidil. They are concerned that salicylic acid in their skincare products might reduce minoxidil's effectiveness.

community Topical Finasteride Selection

in Finasteride/Dutasteride 1 upvotes 3 months ago

A user is seeking advice on choosing the right topical finasteride for hair loss, considering different formats (spray, gel, aqueous solution) and brands (Xyon, Ro, Keeps, Hims Rx Hair Loss Serum, Happy Head Topical Rx Serum). They are also concerned about the optimal strength to minimize side effects while using it with topical minoxidil.

community Topical finasteride & minoxidil

in Finasteride/Dutasteride 1 upvotes 3 months ago

A 20-year-old is using a topical solution with finasteride, minoxidil, and tretinoin for hair thinning. They seek advice on application, duration, and potential results.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 127 upvotes 4 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Topical Dutasteride 0.025% 2ml once a week

in Treatment 10 upvotes 4 months ago

A user discusses using topical dutasteride 0.025% once a week for hair maintenance, alongside fortified minoxidil, RU58841, and Reviv Hair Serum. They seek feedback on the effectiveness of this regimen.

community Worth giving topical fin a chance if oral gave strong depression? 23M

in Finasteride/Dutasteride 1 upvotes 4 months ago

A 23-year-old experienced severe depression and suicidal thoughts from oral finasteride and is considering trying topical finasteride but is worried about similar side effects. They are currently using RU58841 and Minoxidil and are seeking advice on the lowest effective dose of topical finasteride.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 72 upvotes 4 months ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.