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GlossaryTacrolimus (Protopic)

immunosuppressive drug used to treat eczema and prevent organ rejection

Tacrolimus is an immunosuppressive medication commonly used to prevent organ transplant rejection and to treat certain skin conditions like eczema and psoriasis. It works by inhibiting the activity of T-cells, which are part of the immune system, thereby reducing inflammation and immune responses. In dermatology, it is often available as a topical ointment under the brand name Protopic.

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research Polymeric Micelle Nanocarriers for the Cutaneous Delivery of Tacrolimus: A Targeted Approach for the Treatment of Psoriasis

159 citations, July 2014 in “Molecular pharmaceutics”

New micelle nanocarriers deliver Tacrolimus more effectively to skin layers for psoriasis treatment than the current Protopic ointment.

research Severe Lichen Planus With Co-Localization of Vitiligo: A Rare and Unusual Case

June 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

A 13-year-old boy had both lichen planus and vitiligo, suggesting a possible link between the two conditions.

research Safety of Dermatologic Medications in Pregnancy and Lactation

159 citations, March 2014 in “Journal of The American Academy of Dermatology”

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration After Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus

research Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration After Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus

49 citations, March 2014 in “Journal of Investigative Dermatology”

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

research Tacrolimus in Dermatology

35 citations, August 2001 in “Journal of Cutaneous Medicine and Surgery”

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

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community Hair Loss Inflammation Prevention Stack

in Research/Science 46 upvotes 2 weeks ago

The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 62 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.