TLDR No treatment showed clear superiority for lichen planopilaris.
The study retrospectively analyzed 45 cases of lichen planopilaris (LPP) from 2004-2007 to assess therapeutic effectiveness. The majority of patients were white (93%) and female (69%), with an average age of 51 years. Initial treatments included doxycycline, with 27% showing improvement, and hydroxychloroquine, with 41% showing improvement. Mycophenolate mofetil was used after hydroxychloroquine failure, with a 30% improvement rate. The study found no significant differences between treatments and highlighted the need for a prospective, multicenter, randomized, placebo-controlled study to establish effective therapy. Limitations included its retrospective nature and lack of specific end points like percentage of scalp hair loss.
113 citations,
May 2007 in “Journal of the American Academy of Dermatology” The study found that steroids and tetracycline helped treat active Lichen planopilaris, and hair transplants were good for later stages.
8 citations,
January 2018 in “Journal of the American Academy of Dermatology” Diphenylcyclopropenone treatment helps prevent hair loss relapse in alopecia areata patients.
The document concludes that diagnosing female hair loss requires careful examination, with treatments varying by condition and psychological support often necessary.
117 citations,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
20 citations,
October 2013 in “British Journal of Dermatology” The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
66 citations,
January 2010 in “Journal of The American Academy of Dermatology” Mycophenolate mofetil was effective for most patients in treating scarring hair loss, but some had side effects.
