Frontal Fibrosing Alopecia: A Retrospective Analysis of 72 Patients from a German Academic Center

In a retrospective analysis of 72 patients with Frontal Fibrosing Alopecia (FFA), a condition primarily affecting postmenopausal women, a combination therapy of topical high-potency steroids and pimecrolimus was administered to 48 patients. This treatment led to subjective improvement or disease stabilization in 64.6% of these patients after 9 to 12 months. The study also reported a high incidence of hypothyroidism (29.2%) among the patients, which is notably higher than the general population. Despite the limitations of the study, such as its retrospective design and the absence of a control group, the findings suggest that the combination therapy could be an effective treatment for FFA, although future prospective randomized trials are necessary to confirm these results.