Effectiveness of Low-Level Laser Therapy in Lichen Planopilaris

    December 2017 in “ Journal of The American Academy of Dermatology ”
    Pablo Fonda‐Pascual, Óscar M. Moreno‐Arrones, David Saceda‐Corralo, Ana Rita Rodrigues-Barata, Cristina Pindado‐­Ortega, P. Boixeda, Sergio Vañó‐Galván
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    Studysummary This study found that low-level laser therapy may reduce inflammation and increase hair thickness in patients with lichen planopilaris after six months of treatment, though the small sample size limits the findings.
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    The study, conducted on eight Caucasian patients with Lichen Planopilaris (LPP), found that low-level laser therapy (LLLT) could be effective in reducing symptoms and increasing hair thickness in patients with this scarring alopecia. Over six months, patients treated with LLLT showed a significant reduction in the Lichen Planopilaris Activity Index (LPPAI) score by a mean of 0.87 (p=0.012) and an increase in terminal hair thickness by 111.0 µm after three months (p=0.018) and 82.4 µm after six months (p=0.035). Despite these positive results, the study's conclusions are limited by its small sample size, the absence of a control group, and the lack of histological data.
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