Guidelines for the Management of Androgenetic Alopecia (2010)

December 2011 in “ Journal of Dermatology ”

Ryoji Tsuboi, Satoshi Itami, Shigeki Inui, Rie Ueki, Kensei Katsuoka, Sotaro Kurata, Takeshi Kono, Norimitsu Saito, Motomu Manabe, Masashi Yamazaki

androgenetic alopecia topical minoxidil oral finasteride prosthetic hair implantation Rogaine Propecia

TLDR Use minoxidil for hair loss treatment, and finasteride for men.

The 2010 "Guidelines for the management of androgenetic alopecia" provide recommendations for the diagnosis and treatment of hair loss in both men and women. The document recommends the use of topical minoxidil as a first-line treatment for both genders, and oral finasteride for men. The use of prosthetic hair implantation is not recommended due to lack of evidence. The document also mentions various studies and their results to support these recommendations.

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Research cited in this study

24 / 24 results

research Randomized Clinical Trial Comparing 5% and 1% Topical Minoxidil for the Treatment of Androgenetic Alopecia in Japanese Men

29 citations , July 2009 in “Journal of Dermatology”

5% minoxidil works better for hair growth than 1% minoxidil.

Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

research Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

33 citations , December 2008 in “Journal of Dermatology”

Adenosine lotion improves hair growth and thickness in women with hair loss.

research Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11

140 citations , October 2008 in “Nature Genetics”

Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

research Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

89 citations , December 2006 in “Lancet Oncology”

Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.

research Reversal of Androgenetic Alopecia by Topical Ketoconazole: Relevance of Anti-Androgenic Activity

38 citations , September 2006 in “Journal of Dermatological Science”

Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.

research Changes in Hair Weight in Men with Androgenetic Alopecia After Treatment with Finasteride (1 mg Daily): Three- and Four-Year Results

66 citations , June 2006 in “Journal of The American Academy of Dermatology”

Finasteride increases hair weight and count in men with hair loss, with best results after four years.

research Role of Androgen in Mesenchymal Epithelial Interactions in Human Hair Follicle

67 citations , August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.

research Evaluation and Treatment of Male and Female Pattern Hair Loss

203 citations , December 2004 in “Journal of The American Academy of Dermatology”

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

research Safety of Topical Minoxidil Solution: A One-Year, Prospective, Observational Study

26 citations , July 2003 in “Journal of Cutaneous Medicine and Surgery”

Minoxidil solution safely and effectively treats hair loss.

research Current and Novel Methods for Assessing Efficacy of Hair Growth Promoters in Pattern Hair Loss

86 citations , February 2003 in “Journal of The American Academy of Dermatology”

New methods improve how we test hair growth treatments, but challenges like slow hair changes and high costs remain.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia

239 citations , November 2000 in “Journal of The American Academy of Dermatology”

Finasteride doesn't effectively treat hair loss in postmenopausal women.

research Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia

129 citations , October 2000 in “British Journal of Dermatology”

Finasteride helps increase hair growth in men with hair loss.

Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

115 citations , November 1999 in “Journal of The American Academy of Dermatology”

Minoxidil increases hair weight and count temporarily in men with hair loss.

research Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss

187 citations , June 1999 in “Journal of The American Academy of Dermatology”

Finasteride effectively treats frontal hair loss with few side effects.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

research Hair Regrowth

118 citations , April 1998 in “Dermatologic Clinics”

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

research Ketoconazole Shampoo: Effect of Long-Term Use in Androgenic Alopecia

92 citations , January 1998 in “Dermatology”

Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.

research Guidelines of Care for Androgenetic Alopecia

37 citations , September 1996 in “Journal of The American Academy of Dermatology”

Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.

research Androgenetic Alopecia in the Female

82 citations , March 1994 in “Archives of Dermatology”

2% topical minoxidil effectively treats female hair loss with minimal side effects.

research Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women

58 citations , October 1993 in “International Journal of Dermatology”

Minoxidil helps hair growth and reduces shedding in women.

research Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia

67 citations , March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.

research Topical Minoxidil in Early Androgenetic Alopecia

44 citations , March 1987 in “Journal of The American Academy of Dermatology”

Using minoxidil on balding scalps can stimulate hair regrowth and increase blood flow. It's an effective treatment for early hair loss.

research Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness

41 citations , March 1987 in “Journal of The American Academy of Dermatology”

Topical minoxidil effectively treats male pattern baldness and prevents hair loss.

Similar Research

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Guidelines for the Management of Androgenetic Alopecia (2010)

Research cited in this study

research Randomized Clinical Trial Comparing 5% and 1% Topical Minoxidil for the Treatment of Androgenetic Alopecia in Japanese Men

research Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

research Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11

research Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

research Reversal of Androgenetic Alopecia by Topical Ketoconazole: Relevance of Anti-Androgenic Activity

research Changes in Hair Weight in Men with Androgenetic Alopecia After Treatment with Finasteride (1 mg Daily): Three- and Four-Year Results

research Role of Androgen in Mesenchymal Epithelial Interactions in Human Hair Follicle

research Evaluation and Treatment of Male and Female Pattern Hair Loss

research Safety of Topical Minoxidil Solution: A One-Year, Prospective, Observational Study

research Current and Novel Methods for Assessing Efficacy of Hair Growth Promoters in Pattern Hair Loss

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia

research Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

research Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss

research Finasteride in the Treatment of Men with Androgenetic Alopecia

research Hair Regrowth

research Ketoconazole Shampoo: Effect of Long-Term Use in Androgenic Alopecia

research Guidelines of Care for Androgenetic Alopecia

research Androgenetic Alopecia in the Female

research Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women

research Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia

research Topical Minoxidil in Early Androgenetic Alopecia

research Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness

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