Topical Minoxidil in Early Androgenetic Alopecia

March 1987 in “ Journal of The American Academy of Dermatology ”

Kreindler T

topical minoxidil androgenetic alopecia hair regrowth cutaneous blood flow dermatologic events Rogaine balding scalp

Studysummary This study found that both 2% and 3% topical minoxidil were more effective than placebo in promoting hair growth for men with male pattern baldness over 12 months.

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This document compiles studies on the use of topical minoxidil for hair regrowth in early androgenetic alopecia. The studies suggest that minoxidil can stimulate hair regrowth and increase cutaneous blood flow in balding scalps. A study of 150 men found that both 2% and 3% topical minoxidil were effective in promoting hair growth compared to a placebo. Mild and self-limiting dermatologic events were associated with the study drug, but clinically insignificant minoxidil blood levels were observed. Overall, the studies suggest that topical minoxidil can be an effective treatment for early androgenetic alopecia.

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Research cited in this study

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research Topical Minoxidil in Early Male Pattern Baldness

138 citations , August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations , February 1985 in “Archives of Dermatology”

This study found that 32% of patients with hereditary male pattern baldness experienced cosmetically acceptable hair growth after applying topical minoxidil twice daily, with no serious side effects reported.

research Topical Minoxidil for Hair Regrowth

80 citations , September 1984 in “Journal of The American Academy of Dermatology”

In this study, 5% topical minoxidil was observed to promote hair regrowth in some patients with androgenic alopecia, while no regrowth was noted in patients with alopecia areata.