Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

    December 2008 in “ Journal of Dermatology ”
    Hajimu Oura, Masato Iino, Yosuke Nakazawa … Jiro Kishimoto
    Studysummary This study found that 0.75% adenosine lotion significantly improved hair growth and thickness in Japanese women with female pattern hair loss compared to a placebo.
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    Research cited in this study 10

    1. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    2. Phototrichogram Analysis of Japanese Female Subjects with Chronic Diffuse Hair Loss Journal of Investigative Dermatology Symposium Proceedings · 2003
    3. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002
    4. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    5. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    6. A Hair Growth Questionnaire for Use in the Evaluation of Therapeutic Effects in Men Journal of Dermatological Treatment · 1998
    7. Quantitative Estimation of Hair Growth: Androgenetic Alopecia in Women and the Effect of Minoxidil Journal of Investigative Dermatology · 1990
    8. Use of Topical Minoxidil in the Treatment of Male Pattern Baldness Journal of The American Academy of Dermatology · 1987
    9. The Unit Area Trichogram in the Assessment of Androgen-Dependent Alopecia British Journal of Dermatology · 1983
    10. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977