Investigating the Safety and Efficacy of Platelet-Rich Plasma Treatment for Female Androgenetic Alopecia: Review of the Literature

March 2021 in “ Medicina-lithuania ”

Santo Raffaele Mercuri, Giovanni Paolino, M. Di Nicola, Laura Vollono

platelet-rich plasma PRP female androgenetic alopecia AGA hair growth hair density

TLDR PRP treatment may promote hair growth and improve hair density in women with AGA, but more research is needed.

This document is a review of studies on the safety and effectiveness of platelet-rich plasma (PRP) treatment for female androgenetic alopecia (AGA). The studies suggest that PRP may be effective in promoting hair growth and improving hair density in women with AGA, but more research is needed to determine the optimal treatment protocol and establish long-term safety and efficacy. Overall, PRP treatment appears to be a promising option with minimal side effects and high patient satisfaction rates, but larger, well-designed studies are needed to fully evaluate its effectiveness.

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Research cited in this study

58 / 58 results

Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor

research Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor

10 citations , September 2020 in “Archives of Dermatological Research”

Both methods improve hair density and thickness; double-spin may be more effective.

research Platelet-Rich Plasma for Androgenetic Alopecia: Efficacy Differences Between Men and Women

10 citations , August 2020 in “Dermatologic Therapy”

PRP improves hair thickness for both genders, but only increases hair density in men.

A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia

research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia

20 citations , July 2020 in “Expert Opinion on Biological Therapy”

Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.

research Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial

33 citations , July 2020 in “Journal of The American Academy of Dermatology”

PRP treatment improves hair density and thickness for alopecia, but needs more research.

research The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial

18 citations , July 2020 in “Journal of The American Academy of Dermatology”

PRP injections improve hair density and thickness in women with hair loss.

research A Systematic Review of the Effect of Platelet-Rich Plasma on Androgenetic Alopecia in Women

11 citations , June 2020 in “Dermatologic Therapy”

PRP treatment improves hair density and diameter in women with androgenetic alopecia.

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3 citations , January 2020 in “Indian Journal of Dermatology”

Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.

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43 citations , November 2019 in “American Journal of Clinical Dermatology”

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women

research A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women

22 citations , October 2019 in “Dermatologic Surgery”

Both Platelet-Rich Plasma and Minoxidil foam increase hair count in women with hair loss, but Minoxidil is more effective. However, women were more satisfied with Platelet-Rich Plasma treatment.

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Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

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19 citations , June 2019 in “Clinical Drug Investigation”

Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.

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21 citations , June 2019 in “Dermatologic Surgery”

Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.

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7 citations , May 2019 in “Journal of the Formosan Medical Association”

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

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39 citations , March 2019 in “Dermatologic Surgery”

PRP therapy increases hair density for androgenetic alopecia.

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49 citations , February 2019 in “The Journal of Clinical Endocrinology and Metabolism”

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

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12 citations , January 2019 in “International Journal of Trichology”

Trichoscopy is useful for detecting and monitoring androgenetic alopecia.

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Personality traits and anxiety affect hair loss patients' quality of life.

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14 citations , November 2018 in “Journal of Cosmetic Dermatology”

PRP therapy safely improves hair growth in people with hair loss.

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25 citations , April 2018 in “Journal of Cosmetic Dermatology”

PRP injections increase hair density and diameter in female androgenetic alopecia patients.

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15 citations , March 2018 in “Journal of The American Academy of Dermatology”

PRP therapy improves hair density and thickness in AGA patients, even with other treatments.

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Use minoxidil for hair loss treatment; assess results after 6 months.

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19 citations , May 2017 in “Dermatologic Surgery”

Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.

The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

research The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study

52 citations , May 2017 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density and thickness in women with hair loss.

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43 citations , April 2017 in “Experimental Dermatology”

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

research Platelet-Rich Plasma for the Treatment of Female Pattern Hair Loss: A Patient Survey

5 citations , April 2017 in “Dermatologic Surgery”

PRP treatment satisfies 58% of female hair loss patients, with most noticing fuller, thicker hair and less shedding.

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60 citations , September 2016 in “Dermatologic Surgery”

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

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87 citations , September 2016 in “Dermatologic Surgery”

PRP shows potential for treating female hair loss, but more research needed.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

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101 citations , January 2016 in “Journal of Cutaneous and Aesthetic Surgery”

Different types of hair loss need specific treatments, and while many classification systems exist, each has its flaws; more research is needed to refine these systems and treatments.

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26 citations , September 2015 in “Journal of The American Academy of Dermatology”

Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.

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54 citations , December 2014 in “Wound Repair and Regeneration”

PRP injections may improve hair thickness and density in female hair loss patients.

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86 citations , August 2014 in “Journal of The American Academy of Dermatology”

To diagnose hair loss, use a systematic approach including history, exams, and tests.

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107 citations , August 2014 in “Dermatologic Surgery”

PRP injections improve hair thickness for baldness.

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164 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

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270 citations , March 2012 in “Dermatologic Surgery”

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

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15 citations , June 2011 in “British Journal of Dermatology”

No link found between aromatase gene and female hair loss.

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Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

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Spironolactone helps regrow hair in women with hair loss.

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38 citations , May 2009 in “European journal of dermatology/EJD. European journal of dermatology”

TrichoScan® is a reliable tool for measuring hair growth, providing quicker and more consistent results than manual methods.

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TrichoScan helps identify subtle hair thinning in women with androgenetic alopecia.

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129 citations , January 2009 in “International Journal of Trichology”

Trichoscopy can diagnose female hair loss with high accuracy by looking for specific patterns in hair and scalp appearance.

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A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

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Videodermoscopy improves diagnosis of hair and scalp disorders and may reduce scalp biopsies.

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23 citations , April 2006 in “Skin Research and Technology”

The study concluded that a special imaging technique showed women with hair loss have slower hair growth and a faulty hair replacement cycle.

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Some women with common hair loss may develop permanent hair loss.

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Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.

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Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

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Androgenetic alopecia in women needs more research and better management strategies.

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Androgens significantly affect female hair loss, and hormonal treatments may help.

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