Polycystic Ovarian Syndrome: A Comprehensive Review of Symptoms, Diagnosis, and Management

    January 2013 in “ Indian Journal of Dermatology, Venereology and Leprology ”
    Nina Madnani, Kaleem J Khan, Phulrenu Chauhan, Girish Parmar
    From the encyclopedia
    Metformin →

    diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

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    Studysummary This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The 2013 document reviews Polycystic Ovarian Syndrome (PCOS), a complex disorder with symptoms like irregular menses, acne, seborrhea, hirsutism, infertility, and alopecia, and its association with metabolic syndrome, including obesity and insulin resistance. It highlights the importance of a multidisciplinary approach for management, involving various specialists. The review details the diagnostic criteria for PCOS, including hormonal evaluations and ovarian sonography, and discusses the management strategies, which are symptom-based and include lifestyle changes, medications like Metformin, and oral contraceptives. It also covers treatments for specific symptoms such as hirsutism and anovulatory infertility, mentioning the efficacy of spironolactone, flutamide, finasteride, and eflornithine cream for hirsutism, and clomiphene citrate for infertility. The document emphasizes that there is no cure for PCOS and that treatment focuses on long-term symptom management.
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