Polycystic Ovary Syndrome: Diagnosis, Symptoms, and Management
September 2005
in “
Practical diabetes
”
TLDR PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.
Polycystic ovary syndrome (PCOS) was identified as the most common endocrinopathy in women of reproductive age, characterized by chronic ovulatory dysfunction and hyperandrogenism, with a prevalence ranging from 5-21% depending on diagnostic criteria. The pathogenesis involved genetic factors, ovarian and adrenal hyperandrogenism, and insulin resistance. Clinical features included hirsutism, acne, male pattern baldness, menstrual disturbances, and obesity. Diagnosis relied on clinical, biochemical, and ultrasonographic criteria. Treatment focused on weight loss, managing hirsutism, and addressing insulin resistance, with weight loss significantly improving symptoms. Various treatments were discussed, including insulin sensitizers, anti-androgens, eflornithine cream, OCP, and infertility treatments. Regular screening for type 2 diabetes and hypertension was recommended due to associated risks, and patient education and cardiovascular risk management were emphasized.