The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride

    Anik Gupta, Andrew Charrette
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    TLDR Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
    This study evaluated the efficacy and safety of 5α-reductase inhibitors for the treatment of androgenetic alopecia (AGA). The study found that both finasteride and dutasteride were effective in treating hair loss, with dutasteride showing slightly better results. However, there were also potential side effects, including sexual dysfunction and depression, which were more common with finasteride. The study recommends that patients and physicians carefully weigh the benefits and risks of these drugs before deciding on a treatment plan.
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