The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride

    June 2013 in “ Journal of Dermatological Treatment ”
    Anik Gupta, Andrew Charrette
    Image of study
    TLDR Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
    This study evaluated the efficacy and safety of 5α-reductase inhibitors for the treatment of androgenetic alopecia (AGA). The study found that both finasteride and dutasteride were effective in treating hair loss, with dutasteride showing slightly better results. However, there were also potential side effects, including sexual dysfunction and depression, which were more common with finasteride. The study recommends that patients and physicians carefully weigh the benefits and risks of these drugs before deciding on a treatment plan.
    Discuss this study in the Community →

    Research cited in this study

    21 / 21 results

    Related Community Posts Join

    6 / 94 results

      community 1 month of using fin, so happy

      in Progress Pictures  865 upvotes 4 months ago
      User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 2 months ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community Another clueless guy fearmongering and spreading misinformation

      in Chat  251 upvotes 10 months ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 2 years ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

    Related Research

    7 / 7 results