Duration of Finasteride and Dutasteride Treatment Linked to Long-Term Erectile Dysfunction

January 2017 in “ Clinical pharmacist ”

finasteride dutasteride 5α-reductase inhibitors erectile dysfunction persistent erectile dysfunction Propecia Avodart ED

TLDR Long use of finasteride and dutasteride can cause long-term erection problems.

A study conducted on 11,909 men who took the 5α-reductase inhibitors finasteride and dutasteride found that 1.4% of them developed persistent erectile dysfunction (ED) that lasted for at least 90 days after stopping treatment. The duration of exposure to these drugs was a more accurate predictor of persistent ED than other known risk factors such as age, hypertension, and depression. This finding is important for prescribers and patients considering treatment with these inhibitors.

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Related Research

2 / 2 results

research Finasteride for Hirsutism: A Dose Finding Study

8 citations, January 1998 in “PubMed”

Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

75 citations, November 1996 in “Fertility and Sterility”

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.