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    GlossarySkin Permeation (Skin Absorption)

    process where substances pass through skin into bloodstream

    Skin permeation, also known as transdermal absorption or percutaneous absorption, refers to the process by which substances pass through the skin and enter the bloodstream. This process involves the movement of molecules through the outermost layer of the skin (the stratum corneum), into the deeper layers, and eventually into the circulatory system. It is a critical concept in dermatology and pharmacology, particularly for the development of topical medications and transdermal drug delivery systems.

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      community Breezula will hit the market in 2026, Cosmo Pharmaceuticals statement!

      in Product  51 upvotes 2 years ago
      Breezula, a hair loss treatment, is expected to cost around $100 a month and is anticipated to be released in 2026. The effectiveness of Breezula is debated, with some suggesting it loses effectiveness over time and others arguing it maintains hair compared to baseline.

      community Topical Minoxidil is a pain in the ass for diffuse thinners

      in Minoxidil  95 upvotes 3 years ago
      Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community 3 months of minoxidil foam. No fin or derma rolling

      in Minoxidil  700 upvotes 3 years ago
      This user has had success with Minoxidil foam, achieving significant hair growth in three months without using finasteride or derma rolling. They are considering incorporating a DHT reducing strategy such as finasteride in the future.