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    GlossaryCellular Uptake

    process by which cells absorb external substances

    Cellular uptake refers to the process by which cells absorb substances such as nutrients, hormones, and drugs from their surrounding environment. This can occur through various mechanisms like endocytosis, where the cell membrane engulfs the substance, or through transport proteins that facilitate the movement of molecules across the cell membrane. Understanding cellular uptake is crucial for fields like pharmacology and medicine, as it influences how effectively a drug can enter and act within a cell.

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      learn Adenosine

      nucleoside used for hair regrowth stimulant properties

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

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      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  41 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  735 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  7 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community My summation of PP405 - looks promising

      in Research/Science  194 upvotes 1 week ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.