Organic and Biogenic Nanocarriers as Bio-Friendly Systems for Bioactive Compounds Delivery: State-of-the-Art and Challenges

    December 2023 in “ Materials
    Sanja Petrović, Marcela Elisabeta Barbinta-Patrascu
    TLDR Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
    The review discusses the use of organic and biogenic nanocarriers (OBNs) for delivering bioactive compounds. These nanocarriers, which can be naturally sourced or synthesized, include lipids, proteins, polysaccharides, nucleic acids, antibodies, peptides, enzymes, flavonoids, polyphenols, essential oils, plant extracts, natural pigments, and vitamins. They enhance the stability, release characteristics, biocompatibility, and targeted drug delivery of the nanocarriers. The document also highlights the use of polymeric nanoparticles, carbon-based nanomaterials, lipid-based nanocarriers, and nanocarriers derived from animal proteins, plant proteins, and polysaccharides. The paper also discusses the use of living cells and cell derivatives for drug delivery. Despite their potential, challenges exist in developing OBNs, including reproducibility, consistency, cost-effectiveness, biocompatibility, toxicity, control over physicochemical properties, stability, limited loading capacity, biodegradation variability, formulation complexity, low drug loading efficiency, limited targeting efficiency, regulatory challenges, and lack of standardization.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 102 results

      community Is 2-deoxy-D-ribose (2dDR) good for human hair?

      in Research/Science  9 upvotes 9 months ago
      Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).

      community Has anyone tried Exosomes from Musely or somewhere else?

      in Hair Systems  7 upvotes 2 months ago
      Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  865 upvotes 7 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 10 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  139 upvotes 1 year ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

    Related Research

    1 / 1 results