Cosm-Nutraceutical Nanovesicles for Acne Treatment: Physicochemical Characterization and Exploratory Clinical Experimentation

    Sandra Sherif Amer, Maha Nasr, Rasha T.A. Abdel-Aziz, Noha H. Moftah, Amr El Shaer, Elena Polycarpou, Wael Mamdouh, Omaima A. Sammour
    TLDR Vitamin C-based nanovesicles effectively treat acne.
    The study explored the use of vitamin C-based nanovesicles, specifically aspasomes loaded with quercetin, for the treatment of acne vulgaris. These aspasomes were characterized by their size, charge, stability, skin deposition ability, antioxidant potential, and antibacterial activity against Propionibacterium acnes. Essential oils like tea tree and neem were also tested for their potential benefits in acne treatment. The results indicated that the aspasomes were successful in treating acne, suggesting the potential for developing a range of natural nanocosmeceutical delivery systems for other dermatological conditions.
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