Clinical Cosmeceutical Repurposing of Melatonin in Androgenic Alopecia Using Nanostructured Lipid Carriers Prepared with Antioxidant Oils

    September 2018 in “ Expert Opinion on Drug Delivery
    Shymaa Hatem, Maha Nasr, Noha H. Moftah, Maha H. Ragai, Ahmed S. Geneidi, Seham A. Elkheshen
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    Studysummary This study reported that nanostructured lipid carriers with melatonin improved hair density and decreased hair loss in patients with androgenic alopecia, suggesting a promising direction for future treatments.
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    The study explored the repurposing of melatonin for treating androgenic alopecia by using nanostructured lipid carriers (NLCs) prepared with antioxidant oils. The research demonstrated that melatonin-loaded NLCs could enhance hair growth and reduce hair loss. The findings suggested that the antioxidant properties of the oils used in the NLCs contributed to the effectiveness of the treatment. This approach provided a novel and promising method for managing androgenic alopecia.
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