Hair Follicle Changes Following Intense Pulsed Light Axillary Hair Reduction: Histometrical, Histological, and Immunohistochemical Evaluation

    February 2017 in “ Archives of Dermatological Research ”
    Moetaz El‐Domyati, Wael Hosam, Noha H. Moftah, Hamza Abdel Raouf, Selwet M. Saad
    Image of study
    TLDR Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.
    The study, conducted on 21 female volunteers, demonstrated that intense pulsed light (IPL) treatment is effective in reducing axillary hair by inducing hair follicle miniaturization and prolonging the telogen phase. Significant decreases in hair count, hair shaft diameter, and the percentage of terminal anagen follicles were observed, along with reduced expression of proliferation markers PCNA and Ki67 and increased expression of the DNA damage marker P53. This suggests that IPL treatment decreases hair follicle proliferation and may promote apoptosis. The study also noted a significant reduction in hair growth, with hair reduction percentages of 89.26% at one week and 75.90% at one month post-treatment, although there was a slight increase in hair count after one month compared to one week post-treatment. Morphological changes in the hair follicle structures were not observed, indicating the absence of follicular necrosis and resorption.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 272 results

      community Minoxidil seems logistically impossible and impractical to use

      in Minoxidil  136 upvotes 1 year ago
      The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.

      community Embraced baldness. Time to leave this subreddit

      in Chat  873 upvotes 3 months ago
      A user shared their positive experience of embracing baldness after years of trying treatments like Minoxidil and finasteride. They found happiness and confidence by shaving their head, despite some social challenges, and encouraged others to focus on their attitude and seek therapy if needed.

      community Sup Chooms?! How y’all living?!

      in Progress Pictures  972 upvotes 6 months ago
      A 35-year-old shared their 5-month hair regrowth progress, using 0.5mg oral finasteride daily, topical minoxidil/finasteride once daily, derma stamping 1-3 times a week, washing hair daily or every other day with peppermint soap, and using eczema lotion for scalp health. Commenters congratulated the individual on the significant improvement in their hairline.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community RU58841 in powder form from Aliexpress. Is this safe to purchase?

      in Product  3 upvotes 4 months ago
      A user is considering buying RU58841 powder from Aliexpress to mix with Minoxidil for hair loss treatment. Another user warns about the safety concerns of RU58841, especially from unreliable sources, and suggests trying finasteride, oral Minoxidil, and dutasteride first.

    Related Research

    2 / 2 results