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Glossaryp53

regulates cell division and prevents tumor formation

p53, also known as TP53 or Tumor Protein p53, is a crucial gene that produces a protein responsible for regulating cell division and preventing tumor formation. Often referred to as the "guardian of the genome," p53 helps repair damaged DNA or triggers cell death if the damage is irreparable, thereby playing a vital role in cancer prevention.

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research Direct Cellular Reprogramming Enables Development of Viral T Antigen-Driven Merkel Cell Carcinoma in Mice

14 citations , February 2022 in “The Journal of clinical investigation/The journal of clinical investigation”

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

research Keratin 17 in Disease Pathogenesis: From Cancer to Dermatoses

62 citations , October 2018 in “Journal of pathology”

Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.

research The Paradox of p53: What, How, and Why?

64 citations , July 2016 in “Cold Spring Harbor Perspectives in Medicine”

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

research Germline Mutation in ATR in Autosomal-Dominant Oropharyngeal Cancer Syndrome

71 citations , February 2012 in “The American Journal of Human Genetics”

A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.

research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells

25 citations , December 2008 in “The Journal of Urology”

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 2 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.