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regulates cell cycle and prevents tumor formation

p14ARF is a protein that plays a crucial role in regulating the cell cycle and preventing tumor formation. It acts as a tumor suppressor by interacting with another protein called MDM2, which in turn stabilizes the p53 protein, a key player in controlling cell division and apoptosis (programmed cell death). This mechanism helps prevent cells from growing uncontrollably, which is important in cancer prevention.

Related Terms

• Ataxia Telangiectasia and Rad3-related protein
• p21
• Cellular Retinoic Acid-Binding Protein 1
• Cellular Retinoic Acid-Binding Protein 2
• DDB1 and CUL4 associated factor 17
• Androgen Receptor Gene
• p15INK4b
• EDARADD gene