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regulates cell cycle and prevents tumor formation

p14ARF is a protein that plays a crucial role in regulating the cell cycle and preventing tumor formation. It acts as a tumor suppressor by interacting with another protein called MDM2, which in turn stabilizes the p53 protein, a key player in controlling cell division and apoptosis (programmed cell death). This mechanism helps prevent cells from growing uncontrollably, which is important in cancer prevention.

Related Terms

• CDKN2A
• tumor suppressor gene
• cell cycle regulation
• p16