P53-Dependent Transcriptional Regulation of EDA2R and Its Involvement in Chemotherapy-Induced Hair Loss

    April 2010 in “ FEBS Letters ”
    Ran Brosh, Rachel Sarig, Elad Bar Natan … Varda Rotter
    Studysummary In this study, researchers reported that the activation of EDA2R by p53 leads to p53-dependent cell death in cancer cells and is involved in chemotherapy-induced hair loss.
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    Research cited in this study 5

    1. Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies Seminars in Cutaneous Medicine and Surgery · 2009
    2. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    3. Dissecting the Impact of Chemotherapy on the Human Hair Follicle ˜The œAmerican journal of pathology · 2007
    4. Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency Molecular and Cellular Biology · 2004
    5. P53 Involvement in the Control of Murine Hair Follicle Regression American Journal of Pathology · 2001

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