research EDA2R Is Associated with Androgenetic Alopecia
EDA2R gene linked to hair loss.
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research p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss
In this study, researchers reported that the activation of EDA2R by p53 leads to p53-dependent cell death in cancer cells and is involved in chemotherapy-induced hair loss.
research Fine mapping of the human AR/EDA2R locus in androgenetic alopecia
This abstract contains only supplementary material information and reports no new research findings.
research A Tale of Two Haplotypes: The EDA2R/AR Intergenic Region is the Most Divergent Genomic Segment between Africans and East Asians in the Human Genome
In this study, researchers found that two dominant haplotypes in the EDA2R/AR intergenic region have likely been shaped by demographic changes and selection during human evolution, particularly notable in African and non-African populations.
research The Roles of EDA2R in Ageing and Disease
This review discusses the role of the ectodysplasin A2 receptor as a biomarker and driver of ageing related to inflammation, and its potential therapeutic implications, but reports no new clinical findings.
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