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Glossaryoncogene

gene that can cause cancer when mutated or overexpressed

An oncogene is a type of gene that, when mutated or expressed at high levels, can transform a normal cell into a cancerous one. In simpler terms, it's like a switch that, when turned on incorrectly, can lead to uncontrolled cell growth and potentially cancer. For professionals, oncogenes are often derived from proto-oncogenes, which are normal genes involved in cell growth and division, but become harmful when altered.

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research Oncogenes and Morphogens: Intricacies of Targeted Therapy in Cutaneous Basal Cell Carcinoma

December 2017 in “British Journal of Dermatology”

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization

23 citations, May 2013 in “Virology”

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

research Molecular Mechanisms of Viral Oncogenesis in Humans

141 citations, August 2018 in “Nature Reviews Microbiology”

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-Epithelization and Epidermal Growth

research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-Epithelization and Epidermal Growth

19 citations, June 2008 in “Journal of Investigative Dermatology”

HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.

research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer

9 citations, May 2019 in “Experimental Cell Research”

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

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community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.