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    Glossary GLI1

    gene involved in cell growth and development signaling

    GLI1, or Glioma-associated oncogene homolog 1, is a gene that encodes a protein involved in the Hedgehog signaling pathway, which is crucial for cell growth and development. Abnormal activation of GLI1 can lead to uncontrolled cell proliferation and is associated with various cancers, including gliomas.

    Research 10 of 411

    1. GLI2 Is Expressed in Normal Human Epidermis and BCC and Induces GLI1 Expression by Binding to its Promoter Journal of Investigative Dermatology · 2004 · 171 citations
    2. Hedgehog and Gli Signaling in Embryonic Mammary Gland Development Journal of mammary gland biology and neoplasia · 2013 · 25 citations
    3. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors Annals of Dermatology · 2014 · 8 citations
    4. Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis Frontiers in genetics · 2019 · 6 citations
    5. Utility of GLI1 RNA Chromogenic in Situ Hybridization in Distinguishing Basal Cell Carcinoma From Histopathologic Mimics Modern Pathology · 2023 · 3 citations
    6. Rare Gli1+ perivascular fibroblasts promote skin wound repair bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 2 citations
    7. Azelaic acid stimulates catalase activation and promotes hair growth through upregulation of Gli1 and Gli2 mRNA and Shh protein. PubMed · 2020 · 1 citations
    8. The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target Communications biology · 2023
    9. Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway Research Square (Research Square) · 2023
    10. Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1 Proceedings of the National Academy of Sciences · 2000 · 380 citations
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