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    Glossary Artificial Sebum

    synthetic substance mimicking natural skin oils

    Artificial sebum is a synthetic substance designed to mimic the natural oils produced by the sebaceous glands in human skin. It is often used in scientific research and product testing to study skin conditions, hair care products, and the effects of various treatments on the skin and scalp.

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      research Investigation of drug partition property in artificial sebum

      33 citations , June 2007 in “International Journal of Pharmaceutics”
      This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.

      research Diffusion properties of model compounds in artificial sebum

      29 citations , May 2007 in “International journal of pharmaceutics”
      This study found that drug transport through artificial sebum varies depending on the compound, suggesting that sebum-targeted delivery can be optimized by selecting compounds based on their distinct transport profiles in sebum versus skin.

      research Determination of Solute Diffusion Properties in Artificial Sebum

      6 citations , May 2019 in “Journal of pharmaceutical sciences”
      This study found that diffusion coefficients of chemicals in artificial sebum are significantly higher than those in stratum corneum lipids, suggesting the hair follicle may significantly contribute to transdermal permeation.
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      community Best thing you can do for your hair, MCT Oil

       1 upvotes 4 months ago
      MCT oil helps reduce dandruff, flaking, and itching, and may slow hair loss progression. Eliminating sugar and dairy also stabilizes hair loss, while zinc, sugar, and dairy can worsen scalp conditions.

      community Can’t take fin - options/alts?

       5 upvotes 4 years ago
      User seeks non-finasteride hair loss treatments, suggests Eucapil, minoxidil, microneedling, keto shampoo, oral castor oil, and alfatradiol. Reply recommends vitamin D, zinc, pumpkin seed oil, saw palmetto, and high black tea intake, but emphasizes minoxidil and microneedling as most effective.

      community Are there any natural cures? I'm NOT taking finasteride

       5 upvotes 5 years ago
      The user is seeking natural hair loss treatments, avoiding finasteride due to side effects. They mention considering a $1,000 LLT helmet, Nutrafol supplements, and various unproven remedies.

      community How is dht not beneficial to you?

      in Finasteride/Dutasteride  111 upvotes 7 months ago
      DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

      community My personal experience/observations fighting AGA seriously for 5 years

       50 upvotes 1 year ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.
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