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    GlossaryEpidermis (skin layer)

    outermost skin layer providing protection against environmental factors

    The epidermis is the outermost layer of the skin, serving as a protective barrier against environmental factors such as pathogens, UV radiation, and physical injury. It is composed of multiple layers of cells, primarily keratinocytes, which undergo a continuous process of renewal and shedding. This layer also contains melanocytes, which produce melanin, the pigment responsible for skin color.

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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Peppermint

      herb and oil thought to stimulate skin and hair

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

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      community Best Microneedle Lengths To Stimulate Stem Cells

      in Microneedling  18 upvotes 1 year ago
      Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

      community Verteporfin and Microneedling

      in Treatments 6 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Why do I see so many people here recommend microneedling?

      in Microneedling  105 upvotes 1 year ago
      The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.