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GlossarySubcutaneous Tissue (Hypodermis)

layer of fat and connective tissue beneath the skin

Subcutaneous tissue, also known as the hypodermis, is the layer of tissue directly beneath the skin (dermis). It consists primarily of fat and connective tissue, providing insulation, energy storage, and cushioning to protect underlying muscles and bones. This layer also contains larger blood vessels and nerves, playing a crucial role in thermoregulation and sensation.

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research Overexpression of Insulin-Like Growth Factor-1 Induces Hyperplasia, Dermal Abnormalities, and Spontaneous Tumor Formation in Transgenic Mice

147 citations , April 1997 in “Oncogene”

Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.

research From Skin Microrelief to Wrinkles: An Area Ripe for Investigation

108 citations , January 2003 in “Journal of Cosmetic Dermatology”

Wrinkles form due to structural skin changes and vary in type and treatment response.

research Next Generation Human Skin Constructs as Advanced Tools for Drug Development

69 citations , June 2017 in “Experimental Biology and Medicine”

Advanced human skin models improve drug development and could replace animal testing.

research Three-Dimensional Histological Structures of the Human Dermis

52 citations , March 2015 in “Tissue Engineering Part C Methods”

3D images of skin show collagen is evenly spread, but elastic fibers are fewer near hair follicles.

research Anatomy and Function of the Skin

40 citations , January 2016 in “Elsevier eBooks”

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

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community Hair loss research is a money grab

in Chat 217 upvotes 1 month ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community What's the general consensus on microneedling here?

in Microneedling 21 upvotes 1 year ago

The conversation discusses microneedling for hair loss, focusing on optimal needle depth and frequency. Users report varying practices, with some using Minoxidil after microneedling and others suggesting different depths and frequencies based on personal tolerance.