Chromatographic Method for Clobetasol Propionate Determination in Hair Follicles and Different Skin Layers

    August 2016 in “ Biomedical Chromatography ”
    Tamara Ângelo, Marcílio Cunha‐Filho, Guilherme M. Gelfuso, Taís Gratieri
    Studysummary This study developed and validated an HPLC-UV method for accurately quantifying clobetasol propionate in skin and hair follicles, demonstrating its application in in vitro permeation experiments.
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    Research cited in this study 6

    1. Nanocarriers for Optimizing the Balance Between Interfollicular Permeation and Follicular Uptake of Topically Applied Clobetasol to Minimize Adverse Effects Journal of Controlled Release · 2015
    2. Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial American journal of clinical dermatology · 2015
    3. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    4. Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up International Journal of Dermatology · 2014
    5. Clobetasol Propionate, 0.05%, vs Hydrocortisone, 1%, for Alopecia Areata in Children JAMA dermatology · 2013
    6. Comparison of Treatment with Clobetasol Propionate 0.05% and Topical Pimecrolimus 1% in Alopecia Areata Journal of Dermatological Treatment · 2011