Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors

March 2014 in “ Proceedings of the National Academy of Sciences of the United States of America ”

Giacomo Donati, Valentina Proserpio, Beate M. Lichtenberger, Ken Natsuga, Rodney Sinclair, Hironobu Fujiwara, Fiona M. Watt

Wnt/β-catenin signaling adipocyte differentiation epidermis adipogenic factors pre-adipocytes mature adipocytes hair follicle keratinocytes hair cycle

Studysummary This study found that in mice, epidermal Wnt/β-catenin signaling influences adipocyte differentiation and hair growth, suggesting its critical role in synchronizing adipogenesis with the hair growth cycle.

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