Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle

    May 2016 in “ Experimental and Therapeutic Medicine ”
    Chun Hou, Yong Miao, Xue Wang … Zhiqi Hu
    Studysummary In this study, the researchers observed that MMP-2 and MMP-9 significantly fluctuated with the hair growth cycle in mice, suggesting their important role in hair development.
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    Research cited in this study 9

    1. Collagenase IV Plays an Important Role in Regulating Hair Cycle by Inducing VEGF, IGF-1, and TGF-Beta Expression Drug Design Development and Therapy · 2015
    2. Collagenase IV Plays an Important Role in Regulating Hair Cycle by Inducing VEGF, IGF-1, and TGF-β Expression. PubMed · 2015
    3. Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators PLOS Computational Biology · 2014
    4. The Role of Neprilysin in Regulating the Hair Cycle PLoS ONE · 2013
    5. Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    6. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    7. Identification of Clustered Cells in Human Hair Follicle Responsible for MMP-9 Gelatinolytic Activity: Consequences for the Regulation of Hair Growth International Journal of Dermatology · 2001
    8. Hair Cycle-Dependent Expression of Hepatocyte Growth Factor Activator, Other Proteinases, and Proteinase Inhibitors Correlates with the Expression of Hepatocyte Growth Factor in Rat Hair Follicles Journal of Investigative Dermatology Symposium Proceedings · 1999
    9. Soluble and Insoluble Collagen and Elastin in the Rat Hair Cycle Archives of Dermatological Research · 1979