A Matter of Life and Death: Self-Renewal in Stem Cells

December 2012 in “ EMBO Reports ”

Elaine Fuchs, Ting Chen

self-renewal hair follicle stem cells HFSCs stem cell niche transplantation assays lineage-tracing experiments asymmetrical division symmetrical division microenvironment Hmga2 let-7b microRNA Runx1 Tbx1 lentiviruses shRNAs

Studysummary This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.

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