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    Glossary Self-Renewal

    process where stem cells divide to produce identical stem cells

    Self-renewal is the process by which stem cells divide to produce more stem cells, maintaining their undifferentiated state. This ability is crucial for tissue regeneration and repair, as it ensures a continuous supply of stem cells that can differentiate into various cell types needed for growth and healing.

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    Research 10 of 1000+

    1. A matter of life and death: self‐renewal in stem cells EMBO Reports · 2012 · 150 citations
    2. 1314 Advanced age impairs self-renewal and biases fate choice of hair follicle dermal stem cells Journal of Investigative Dermatology · 2018
    3. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis Cell Stem Cell · 2016 · 106 citations
    4. OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases Stem Cell Research & Therapy · 2019 · 57 citations
    5. ROR2 regulates self-renewal and maintenance of hair follicle stem cells Nature Communications · 2022 · 16 citations
    6. 653 Substance P ameliorates epidermal thickness, basal cell density, and asymmetric stem cell self-renewal in skin with decreased sensory innervation Journal of Investigative Dermatology · 2024
    7. Regulation of self-renewal in colorectal cancer cell models Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) · 2014
    8. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury Cell Reports · 2023 · 46 citations
    9. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 2 citations
    10. ZO-1 boosts the in vitro self-renewal of pre-haematopoietic stem cells from OCT4-reprogrammed human hair follicle mesenchymal stem cells through cytoskeleton remodeling Stem Cell Research & Therapy · 2024
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