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    Glossary SOX2

    gene crucial for stem cell pluripotency and tissue development

    SOX2 is a gene that plays a crucial role in maintaining the self-renewal and pluripotency of stem cells, meaning it helps stem cells stay in a state where they can develop into different types of cells. It is also involved in the development of various tissues, including the nervous system and hair follicles, making it significant in both regenerative medicine and understanding conditions like alopecia.

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    Research 10 of 740

    1. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis Development · 2009 · 338 citations
    2. The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice Proceedings of the National Academy of Sciences · 2009 · 73 citations
    3. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011 · 68 citations
    4. Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ iScience · 2020 · 22 citations
    5. SKPing a Hurdle: Sox2 and Adult Dermal Stem Cells Cell stem cell · 2009 · 11 citations
    6. Sox2 in the dermal papilla regulates hair follicle pigmentation Cell reports · 2022 · 9 citations
    7. Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells in Vivo · 2021 · 4 citations
    8. Keratin 75 Is a Component of the LINC Complex and Has an Essential Role in Mediating the SOX2 Rapid Healing Response during Wound Repair 2022 · 3 citations
    9. SOX2 in the Skin Elsevier eBooks · 2015 · 1 citations
    10. A Low Dose of Rapamycin Promotes Hair Cell Differentiation by Enriching SOX2+ Progenitors in the Neonatal Mouse Inner Ear Organoids. PubMed · 2024
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