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GlossaryOCT4

protein crucial for maintaining embryonic stem cell pluripotency

OCT4, also known as Octamer-binding transcription factor 4 or POU5F1, is a protein that plays a crucial role in maintaining the self-renewal and pluripotency of embryonic stem cells. It acts as a transcription factor, meaning it helps regulate the expression of genes that are essential for the development and differentiation of cells. This protein is significant in both developmental biology and regenerative medicine, as it helps scientists understand how cells can be reprogrammed to an undifferentiated state.

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research Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4

15 citations, January 2015 in “Stem cells international”

Human hair follicle stem cells can be turned into red blood cells.

research Role of OCT4 in the Regulation of FSH-Induced Granulosa Cell Growth in Female Mice

14 citations, January 2020 in “Frontiers in Endocrinology”

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes

research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes

160 citations, January 2017 in “Development”

Blood vessels and specific genes help turn cartilage into bone when bones heal.

research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2

123 citations, November 2012 in “Stem cells”

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

research PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

26 citations, August 2019 in “Stem Cell Research & Therapy”

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

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community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 246 upvotes 2 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.