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GlossaryOCT4

protein crucial for maintaining embryonic stem cell pluripotency

OCT4, also known as Octamer-binding transcription factor 4 or POU5F1, is a protein that plays a crucial role in maintaining the self-renewal and pluripotency of embryonic stem cells. It acts as a transcription factor, meaning it helps regulate the expression of genes that are essential for the development and differentiation of cells. This protein is significant in both developmental biology and regenerative medicine, as it helps scientists understand how cells can be reprogrammed to an undifferentiated state.

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research OCT4 Maintains Self-Renewal and Reverses Senescence in Human Hair Follicle Mesenchymal Stem Cells Through the Downregulation of p21 by DNA Methyltransferases

57 citations , January 2019 in “Stem Cell Research & Therapy”

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

research Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4

15 citations , January 2015 in “Stem cells international”

Human hair follicle stem cells can be turned into red blood cells.

research Role of OCT4 in the Regulation of FSH-Induced Granulosa Cell Growth in Female Mice

14 citations , January 2020 in “Frontiers in Endocrinology”

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

ZO-1 Boosts the In Vitro Self-Renewal of Pre-Haematopoietic Stem Cells from OCT4-Reprogrammed Human Hair Follicle Mesenchymal Stem Cells Through Cytoskeleton Remodeling

research ZO-1 Boosts the In Vitro Self-Renewal of Pre-Haematopoietic Stem Cells from OCT4-Reprogrammed Human Hair Follicle Mesenchymal Stem Cells Through Cytoskeleton Remodeling

December 2024 in “Stem Cell Research & Therapy”

ZO-1 helps hair follicle stem cells renew better by changing their structure.

research Study of the Expression of Pluripotency Markers in Idiopathic Inflammatory Bowel Diseases

November 2018

OCT4B1 and SOX-2 levels are higher in Crohn's and ulcerative colitis patients, possibly aiding tissue repair.

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community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 250 upvotes 3 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.