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GlossaryLipogenesis

biological process converting excess carbs into stored fat

Lipogenesis is the biological process by which the body converts excess carbohydrates into fatty acids, which are then stored as fat. This process primarily occurs in the liver and adipose (fat) tissue and is crucial for energy storage and maintaining energy balance in the body.

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research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells

44 citations, January 2013 in “BMC Dermatology”

TGFβ signaling prevents sebaceous gland cells from producing fats.

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community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 8 months ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 4 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.