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    Glossary Lipogenesis

    biological process converting excess carbs into stored fat

    Lipogenesis is the biological process by which the body converts excess carbohydrates into fatty acids, which are then stored as fat. This process primarily occurs in the liver and adipose (fat) tissue and is crucial for energy storage and maintaining energy balance in the body.

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    Research 30 of 462

    1. Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes Proceedings of the National Academy of Sciences · 2002 · 284 citations
    2. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    3. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    4. Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway Frontiers in Bioengineering and Biotechnology · 2021 · 13 citations
    5. Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway Molecular Medicine · 2025 · 4 citations
    6. Inhibition of lipogenesis and sebum secretion for <i>Lotus corniculatus</i> seed extract in vitro and in vivo International Journal of Cosmetic Science · 2022 · 1 citations
    7. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    8. 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    9. Vitisin A Outperforms Cyanidin-3-O-Glucoside in Triglyceride Reduction by Modulating Hepatic Lipogenesis and Fatty Acid β-Oxidation International Journal of Molecular Sciences · 2025 · 5 citations
    10. New developments in our understanding of acne pathogenesis and treatment Experimental dermatology · 2009 · 466 citations
    11. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    12. Mechanistic target of rapamycin (mTOR) expression is increased in acne patients' skin Experimental Dermatology · 2015 · 74 citations
    13. Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne 2009 · 65 citations
    14. 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes Endocrinology · 2015 · 54 citations
    15. Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis Lipids · 2004 · 46 citations
    16. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    17. Insulin Resistance, Acanthosis Nigricans, and Polycystic Ovaries Associated with a Circulating Inhibitor of Postbinding Insulin Action The Journal of Clinical Endocrinology & Metabolism · 1985 · 24 citations
    18. The Organ-Maintained Human Sebaceous Gland Dermatology · 1998 · 16 citations
    19. Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids FASEB bioAdvances · 2021 · 13 citations
    20. Possible intermediary role of ghrelin in seborrhea Medical Hypotheses · 2015 · 4 citations
    21. 2063-LB: Transgenic Erythropoietin Overexpression Inhibits Dermal Fat Formation and HIF1a in the Skin and Causes Telogen Effluvium in Mouse Pups during the First Hair Cycle Diabetes · 2024
    22. Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1 ˜The œFASEB journal · 2023
    23. 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    24. PHARMACOLOGICAL BASIS FOR CLINICAL USE OF ANTIANDROGENS Elsevier eBooks · 1983
    25. Role of insulin resistance and diet in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 39 citations
    26. Ligand‐independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice Experimental Dermatology · 2013 · 22 citations
    27. 0952 Spatial transcriptomics reveal compartmentalized dysregulation of lipid metabolism in acne vulgaris Journal of Investigative Dermatology · 2025
    28. Role of insulin, insulin‐like growth factor‐1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris Experimental dermatology · 2009 · 200 citations
    29. Regulation of the metabolic phenotype of human hepatocytes by glucocorticoids and androgens University of Birmingham Institutional Research Archive (University of Birmingham) · 2016
    30. 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2) Journal of Investigative Dermatology · 2018