Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses

    August 2018 in “ Journal of Investigative Dermatology ”
    Magdolna Szántó, Attila Oláh, Attila Gábor Szöllősi … Balázs István Tóth
    Studysummary This study found that TRPV3 activation in human sebocytes inhibits lipid synthesis and triggers proinflammatory cytokine expression, suggesting a role in the pathogenesis of dry skin-associated inflammatory dermatoses.
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    Research cited in this study 3

    1. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017
    2. Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2011
    3. Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv · 2011