Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases

    December 2022 in “ Cells ”
    Robert Ramer, Burkhard Hinz
    Studysummary This review examines the role of cannabinoid compounds in treating various skin conditions and suggests their potential as systemic and topical therapies, but it reports no new experimental results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 29

    1. Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin International journal of molecular sciences · 2021
    2. Cannabinoids for Skin Diseases and Hair Regrowth Journal of Cosmetic Dermatology · 2021
    3. Regulatory Effect of Cannabidiol on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells Journal of pharmacopuncture · 2021
    4. Hair Regrowth with Cannabidiol (CBD)-Rich Hemp Extract – A Case Series Cannabis · 2021
    5. Gene Variants Associated With Acne Vulgaris Presentation and Severity: A Systematic Review and Meta-Analysis BMC Medical Genomics · 2021
    6. Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle Experimental Dermatology · 2021
    7. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    8. Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis Skin appendage disorders · 2020
    9. Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes PloS one · 2019
    10. The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar Versus Hair Growth Inhibitory Micromolar Effects Journal of Investigative Dermatology · 2019
    11. Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes bioRxiv (Cold Spring Harbor Laboratory) · 2019
    12. Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System Molecules/Molecules online/Molecules annual · 2019
    13. Acne, the Skin Microbiome, and Antibiotic Treatment American journal of clinical dermatology · 2019
    14. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018
    15. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    16. Androgenetic Alopecia: Drug Safety and Therapeutic Strategies Expert Opinion on Drug Safety · 2018
    17. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017
    18. Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases? BioEssays · 2014
    19. A Novel Control of Human Keratin Expression: Cannabinoid Receptor 1-Mediated Signaling Down-Regulates the Expression of Keratins K6 and K16 in Human Keratinocytes In Vitro and In Situ PeerJ · 2013
    20. Evaluation of Perifollicular Inflammation of Donor Area During Hair Transplantation in Androgenetic Alopecia and Its Comparison With Controls International Journal of Trichology · 2013
    21. Actinic Keratosis: A Clinical and Epidemiological Review Anais Brasileiros de Dermatologia · 2012
    22. Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin Journal of Allergy and Clinical Immunology · 2012
    23. Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2011
    24. Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv · 2011
    25. The Pathogenesis of Primary Cicatricial Alopecias The American Journal of Pathology · 2010
    26. New Developments in Our Understanding of Acne Pathogenesis and Treatment Experimental dermatology · 2009
    27. Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth Acta dermato-venereologica · 2000
    28. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993
    29. The Inheritance Of Common Baldness: To Be Or Not To Be? Journal of the American Academy of Dermatology · 1984