Cannabidiol in Skin Health: A Comprehensive Review of Topical Applications in Dermatology and Cosmetic Science

August 2025 in “ Biomolecules ”

Aura Rusu, Anca Daniela Fărcaș, Octavia-Laura Moldovan, Corneliu Tanase

cannabidiol CBD anti-inflammatory antioxidant antimicrobial acne eczema psoriasis hair regrowth hair loss topical applications advanced delivery systems

Studysummary This review discusses the potential topical benefits of cannabidiol in dermatology and cosmetics, highlighting its diverse effects and therapeutic roles but reports no new clinical results, emphasizing the need for further research.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The review highlights the potential of cannabidiol (CBD) in dermatology and cosmetic science, emphasizing its anti-inflammatory, antioxidant, and antimicrobial properties. CBD shows promise in managing skin conditions like acne, eczema, and psoriasis, and may also benefit hair health by promoting regrowth and addressing hair loss. Despite promising results, challenges such as poor water solubility and regulatory variability hinder its widespread use. The review underscores the need for more extensive clinical trials to fully understand CBD's mechanisms and optimize its formulations for topical applications. Advanced delivery systems are being developed to enhance CBD's efficacy, but further research is necessary to establish its safety and therapeutic potential in dermatology.

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9 / 9 results

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Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

research Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

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research Targeting Cutaneous Cannabinoid Signaling in Inflammation: A Highway to Heal?

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