Hair Regrowth With Novel Hemp Extract: A Case Series

January 2023 in “ International Journal of Trichology ”

GregoryLuke Smith

hemp extract CBD THCV CBDV androgenetic alopecia topical hemp extract hair regrowth finasteride minoxidil hemp oil cannabidiol tetrahydrocannabivarin cannabidivarin AGA Propecia Rogaine

From the encyclopedia

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

cannabidiol →

Studysummary In a case series, this study reported significant hair regrowth in both men and women with androgenetic alopecia using a topical hemp extract high in CBD, THCV, and CBDV over six months.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This case series study investigated the effects of a novel hemp extract containing CBD, THCV, and CBDV on hair regrowth in 31 subjects with androgenetic alopecia (AGA). Over 6 months, subjects applied a topical hemp extract daily, resulting in a significant average hair count increase of 246% in men and 127% in women. All subjects experienced some degree of hair regrowth, with no adverse effects reported. Psychosocial perceptions were positive, with all subjects feeling "happy" or "very happy" about the results. Independent photographic reviews confirmed "mild" to "extensive" improvements in scalp coverage. The study suggests that the hemp extract works through mechanisms different from traditional treatments like finasteride and minoxidil, potentially offering synergistic benefits when used together.

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Research cited in this study

16 / 16 results

research Hair Regrowth with Cannabidiol (CBD)-Rich Hemp Extract – A Case Series

7 citations , April 2021 in “Cannabis”

In this study, topical CBD significantly increased hair count by 93.5% over six months in individuals with androgenetic alopecia, with no adverse effects reported.

The Efficacy and Safety of Finasteride Combined with Topical Minoxidil for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research The Efficacy and Safety of Finasteride Combined with Topical Minoxidil for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

8 citations , March 2020 in “Aesthetic Plastic Surgery”

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research A Review of the Treatment of Male Pattern Hair Loss

53 citations , February 2020 in “Expert Opinion on Pharmacotherapy”

This review discusses pharmacologic and non-pharmacologic treatments for androgenetic alopecia, noting that current medications like finasteride and minoxidil can slow hair loss but only partially restore hair growth, with early treatment offering better outcomes.

research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System

142 citations , March 2019 in “Molecules/Molecules online/Molecules annual”

This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.

A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia

research A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia

43 citations , July 2018 in “Journal of The European Academy of Dermatology and Venereology”

This study found that a topical solution combining 0.25% finasteride with 3% minoxidil significantly improved hair growth, as measured by hair density, diameter, and global assessment, in men with androgenetic alopecia, compared to 3% minoxidil alone, over 24 weeks without systemic adverse effects reported.

research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

178 citations , April 2017 in “Journal of The American Academy of Dermatology”

This systematic review and meta-analysis found that minoxidil, finasteride, and low-level laser light therapy significantly improve hair growth in men with androgenetic alopecia, while minoxidil is also effective for women, compared to placebo.

Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey

research Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey

37 citations , February 2017 in “Anais Brasileiros De Dermatologia”

In this study, researchers found that the prevalence of androgenetic alopecia was higher in their sample compared to other studies in Asian and Caucasian populations, and it was linked with age-related severity.

research Peppermint Oil Promotes Hair Growth Without Toxic Signs

30 citations , December 2014 in “Toxicological Research”

This study found that 3% peppermint oil significantly enhanced hair growth in C57BL/6 mice, showing increased dermal thickness, follicle number, and follicle depth compared to other treatments.

research Hair Through the Female Life Cycle

40 citations , December 2011 in “British Journal of Dermatology”

This article reviews how chronological aging affects female scalp hair growth and suggests that multiple factors, including environmental influences, contribute to female pattern hair loss; no new clinical results are presented.

research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss

185 citations , March 2011 in “The Journal of Sexual Medicine”

This study found that 94% of healthy men reported low libido and 92% reported erectile dysfunction as persistent sexual side effects after using finasteride for male pattern hair loss, with these effects lasting on average 40 months post-discontinuation.

research Finasteride Treatment of Hair Loss in Women

29 citations , May 2010 in “Annals of Pharmacotherapy”

This review discusses the limited objective evidence for using finasteride in women with alopecia, suggesting that it could be considered for those who don't benefit from minoxidil, but reports no new clinical results.

research Minoxidil: Mechanisms of Action on Hair Growth

397 citations , February 2004 in “British Journal of Dermatology”

This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.

research Androgens and Alopecia

165 citations , December 2002 in “Molecular and Cellular Endocrinology”

This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.

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59 citations , August 1998 in “International Journal of Dermatology”

Genetics and hormones cause hair loss; finasteride treats it safely.

research The Psychological Effects of Androgenetic Alopecia in Men

192 citations , June 1992 in “Journal of The American Academy of Dermatology”

Hair loss can cause low self-esteem, anxiety, and depression in men.

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11 citations , September 1988 in “Annals of Plastic Surgery”

This review discusses topical minoxidil for hair growth, reporting about one-third of users gain new hair, noting diminished effects after a year and increased hair loss if stopped, but provides no new experimental results.