In Vitro, Ex Vivo, and Clinical Evaluation of Anti-Aging Gel Containing EPA and CBD

    Guy Cohen, Jeannette Jakus, M. Portillo, Raanan Gvirtz, Navit Ogen‐Shtern, Eldad Silberstein, T Ayzenberg, Sharon Rozenblat
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    TLDR The gel with CBD and EPA reduced wrinkles, improved skin hydration and elasticity, and had strong anti-aging effects.
    The research evaluated the anti-aging efficacy of a topical gel containing cannabidiol (CBD) and eicosapentaenoic acid (EPA) through in vitro, ex vivo, and clinical trials. The clinical trial involved 34 subjects aged 45-65. The gel showed potential in preventing, minimizing, and reversing the effects of accelerated aging, as evidenced by increased skin moisture, reduced ROS formation, and improved dermatitis. The gel also demonstrated anti-inflammatory action. The study concluded that the gel has significant anti-aging effects, with high patient satisfaction reported, and recommended long-term application for full benefits.
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