Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

    January 2020 in “ Skin appendage disorders ”
    Colombina Vincenzi, Antonella Tosti
    Studysummary This study found that a shampoo containing 0.075% broad-spectrum cannabidiol significantly reduced scalp inflammation and symptoms in subjects with mild to moderate scalp psoriasis or seborrheic dermatitis within two weeks.
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    Research cited in this study 11

    1. The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar Versus Hair Growth Inhibitory Micromolar Effects Journal of Investigative Dermatology · 2019
    2. Topical Ketoconazole: A Systematic Review of Current Dermatological Applications and Future Developments Journal of Dermatological Treatment · 2019
    3. Scalp Condition Impacts Hair Growth And Retention Via Oxidative Stress International journal of trichology · 2018
    4. Serum Biotin Levels in Women Complaining of Hair Loss International Journal of Trichology · 2016
    5. The Role of Oxidative Damage in Poor Scalp Health: Ramifications to Causality and Associated Hair Growth International Journal of Cosmetic Science · 2015
    6. Investigation of Oxidative Stress in Patients with Alopecia Areata and Its Relationship with Disease Severity, Duration, Recurrence, and Pattern Clinical and experimental dermatology · 2014
    7. Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro British Journal of Dermatology · 2014
    8. Oxidative Stress in Alopecia Areata: A Case-Control Study American Journal of Clinical Dermatology · 2013
    9. Hair and Scalp Dermatoscopy Journal of The American Academy of Dermatology · 2012
    10. Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations International Journal of Cosmetic Science · 2002
    11. Psoriasis of the Scalp: Diagnosis and Management American Journal of Clinical Dermatology · 2001