Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

In 2020, a study involving 50 participants with mild to moderate scalp psoriasis or seborrheic dermatitis found that a shampoo containing 0.075% broad-spectrum cannabidiol significantly reduced scalp inflammation and symptoms within 14 days of use. Severity scores for inflammation and scaling reduced from 2.3 ± 0.1, 2.6 ± 0.1, and 3.6 ± 0.1 to 0.5 ± 0.05, 0.8 ± 0.05, and 0.6 ± 0.05 respectively. Itching and burning scores also significantly reduced from 6.9 ± 0.1 and 4.5 ± 0.1 to 1.5 ± 0.05 and 1.0 ± 0.05 respectively. The shampoo was well-tolerated and satisfaction among subjects was high. This suggests that cannabidiol-containing shampoo could be a potential treatment for scalp conditions like psoriasis and seborrheic dermatitis.