The Role of Oxidative Damage in Poor Scalp Health: Ramifications to Causality and Associated Hair Growth

    James R. Schwartz, James P. Henry, Kathy Kerr, Haruko Mizoguchi, L. Li
    TLDR Treating scalp issues with anti-dandruff shampoo improves hair health.
    The study, involving 300 subjects over 24 weeks, demonstrated that oxidative stress significantly impacted scalp health and hair quality, particularly in conditions like dandruff and seborrhoeic dermatitis. Higher levels of oxidative stress markers, such as HODE, were found in affected individuals. Treatment with a potentiated ZPT shampoo significantly reduced oxidative stress and improved both scalp and hair health, achieving over 70% reduction in HODE levels after 16 weeks. The findings highlighted the importance of managing oxidative stress to improve scalp conditions and hair quality, as damage from oxidative stress in pre-emergent hair cannot be repaired once the hair has emerged.
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