215 citations
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March 2018 in “Archives of Toxicology” This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.
210 citations
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May 2006 in “The FASEB journal” This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.
58 citations
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October 2016 in “Journal of Investigative Dermatology” This study found that activating Nrf2 in human hair follicles significantly reduced oxidative stress, lipid peroxidation, and protected against hair growth inhibition, suggesting a protective role for Nrf2 against redox insult in this context.
53 citations
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October 2014 in “Free radical biology & medicine” This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.
24 citations
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November 2015 in “International Journal of Cosmetic Science” This study demonstrated that oxidative stress contributes to dandruff, and using a potentiated ZPT shampoo improves scalp and hair condition by reducing oxidative stress.