Bioactives in Nutricosmetics: A Focus on Caffeine from Tea to Coffee

August 2024 in “ Cosmetics ”

Cristina Blanco-Llamero, Hugo F. Macário, Beatriz N. Guedes, Faezeh Fathi, M. Beatriz P.P. Oliveira, Eliana B. Souto

caffeine androgenic alopecia antioxidant UV blockers nanosized delivery systems nutricosmetics bioactives skin disorders skin health hair loss sun protection nano delivery systems cosmetic bioactives skin care

TLDR Caffeine is beneficial for skin and hair treatments but needs better delivery methods to penetrate deeper skin layers.

The review article "Bioactives in Nutricosmetics: A Focus on Caffeine from Tea to Coffee" discusses the multifaceted benefits of caffeine in skincare and hair health, emphasizing its antioxidant, anti-inflammatory, and antimicrobial properties. Caffeine is effective in treating skin disorders and androgenic alopecia, with results comparable to minoxidil. The article highlights the potential of using sustainable by-products like coffee silverskin for caffeine extraction and the use of nanosized delivery systems to improve skin penetration. Studies show caffeine's efficacy in UV protection, cellulite reduction, and anti-aging, underscoring its versatility in cosmetic applications. Continued research is expected to drive further innovation in caffeine-based formulations.

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Research cited in this study

11 / 11 results

Assessment of the Efficacy and Tolerability of a Topical Formulation Containing Caffeine and Procapil 3% for Improvement of Male Pattern Hair Loss

research Assessment of the Efficacy and Tolerability of a Topical Formulation Containing Caffeine and Procapil 3% for Improvement of Male Pattern Hair Loss

November 2023 in “Journal of Cosmetic Dermatology”

The topical treatment with caffeine and Procapil 3% improved male pattern hair loss and was well tolerated after 12 weeks.

research Complementary and Alternative Supplements: A Review of Dermatologic Effectiveness for Androgenetic Alopecia

September 2023 in “Baylor University Medical Center Proceedings”

Some alternative supplements might help with hair loss due to androgenetic alopecia.

A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia

research A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia

May 2023 in “PubMed”

Redensyl, saw palmetto, and biotin with platelet-rich plasma is a better treatment for hair loss than Procapil with platelet-rich plasma.

research Scalp Application of Antioxidants Improves Scalp Condition and Reduces Hair Shedding in a 24-Week Randomized, Double-Blind, Placebo-Controlled Clinical Trial

6 citations, August 2021 in “International Journal of Cosmetic Science”

Using antioxidants on the scalp can make it healthier and decrease hair loss.

research Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution

1 citations, February 2020 in “PubMed”

The topical solution improved hair density and appearance in men with androgenetic alopecia.

research Coffee Silverskin: A Review on Potential Cosmetic Applications

61 citations, January 2018 in “Cosmetics”

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

research An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

21 citations, January 2017 in “Skin Pharmacology and Physiology”

Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.

research A Review of the Use of Biotin for Hair Loss

78 citations, January 2017 in “Skin appendage disorders”

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

Nanocrystals of Medium Soluble Actives: Novel Concept for Improved Dermal Delivery and Production Strategy

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The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance

research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance

16 citations, September 2018 in “Journal of Ethnopharmacology”

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth

research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients

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The model and estimator can predict drug exposure in kidney transplant patients well.

Bioactives in Nutricosmetics: A Focus on Caffeine from Tea to Coffee

Research cited in this study

research Assessment of the Efficacy and Tolerability of a Topical Formulation Containing Caffeine and Procapil 3% for Improvement of Male Pattern Hair Loss

research Complementary and Alternative Supplements: A Review of Dermatologic Effectiveness for Androgenetic Alopecia

research A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia

research Scalp Application of Antioxidants Improves Scalp Condition and Reduces Hair Shedding in a 24-Week Randomized, Double-Blind, Placebo-Controlled Clinical Trial

research Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution

research Coffee Silverskin: A Review on Potential Cosmetic Applications

research An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

research A Review of the Use of Biotin for Hair Loss

research Nanocrystals of Medium Soluble Actives: Novel Concept for Improved Dermal Delivery and Production Strategy

research Caffeine’s Mechanisms of Action and Its Cosmetic Use

research The Role of Hair Follicles in the Percutaneous Absorption of Caffeine

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