Caffeine as an Active Molecule in Cosmetic Products for Hair Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology

    January 2025 in “ Molecules ”
    Ewelina Szendzielorz, Radosław Śpiewak
    TLDR Caffeine may help with hair loss, but more research is needed to confirm its effectiveness.
    Caffeine is being explored as a treatment for hair loss due to its ability to penetrate hair follicles effectively, increase cAMP levels, and act as an antioxidant, potentially counteracting hair follicle miniaturization. It targets hair follicle structures, stimulating cell growth and survival pathways. While clinical studies suggest caffeine's effectiveness, they often lack rigorous design, such as control groups and clear concentration data. Despite its promising safety profile, further research with robust study designs is needed to confirm caffeine's efficacy in managing hair loss, particularly in conditions like androgenetic alopecia.
    Discuss this study in the Community →

    Research cited in this study

    37 / 37 results

    Related Community Posts Join

    6 / 507 results

      community Ultimate Stack without nuking your gender (you'll go broke)

      in Treatment  86 upvotes 5 months ago
      A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

      community Gains or growth? Three months in

      in Is this regrowth?  146 upvotes 2 weeks ago
      The user is using topical minoxidil twice daily for hair regrowth and is hesitant to use finasteride due to concerns about hormonal effects. The conversation includes mixed opinions on the effectiveness of the treatment and suggestions to use a DHT blocker for better results.

      community 18M 8 months progress 40mg daily dut stack

      in Progress Pictures  113 upvotes 6 days ago
      An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

      community 3 month progress on Minoxidil 5% only.

      in Is this regrowth?  1040 upvotes 1 year ago
      A user is pleased with their hair regrowth after 3 months using Minoxidil 5%. They plan to start Finasteride upon returning home, and others discuss the importance of consistency and patience with hair loss treatments.

      community Finasteride two years results from horrible shed

      in Progress Pictures 2 years ago
      This user experienced severe hair loss, but was able to successfully treat it with finasteride over a two year period. Despite experiencing multiple shedding cycles while on the medication, Mission5896 reported that their hair continued to get thicker and stronger. Additionally, they tried both minoxidil orally and topically, but only found success with finasteride.

    Related Research

    7 / 7 results