The Dynamics of the Skin’s Immune System

    April 2019 in “ International Journal of Molecular Sciences ”
    Alan V. Nguyen, Athena M. Soulika
    Studysummary This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 22

    1. Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds Nature Communications · 2019
    2. The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model International Journal of Molecular Sciences · 2019
    3. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    4. Macrophages Regulate Schwann Cell Maturation After Nerve Injury Cell Reports · 2018
    5. Human αβ and γδ T Cells in Skin Immunity and Disease Frontiers in immunology · 2018
    6. Regulatory T Cells in Autoimmune Skin Diseases Experimental Dermatology · 2018
    7. Regulatory T Cells Are Required for Normal and Activin-Promoted Wound Repair in Mice European Journal of Immunology · 2018
    8. Scarless Wound Healing: Transitioning from Fetal Research to Regenerative Healing Wiley Interdisciplinary Reviews-Developmental Biology · 2018
    9. Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance Immunology · 2017
    10. Toll-Like Receptor Function in Acute Wounds Advances in wound care · 2017
    11. The Role of Macrophages in Skin Homeostasis Pflügers Archiv - European Journal of Physiology · 2017
    12. Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions Advances in wound care · 2016
    13. Skin CD4+ Memory T Cells Exhibit Combined Cluster-Mediated Retention and Equilibration with the Circulation Nature communications · 2016
    14. Expression of Dermcidin in Sebocytes Supports a Role for Sebum in the Constitutive Innate Defense of Human Skin Journal of Dermatological Science · 2015
    15. Hair Follicle-Derived IL-7 and IL-15 Mediate Skin-Resident Memory T Cell Homeostasis and Lymphoma Nature medicine · 2015
    16. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    17. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    18. Defining Dermal Adipose Tissue Experimental Dermatology · 2014
    19. Mechanisms Regulating Skin Immunity and Inflammation Nature Reviews Immunology · 2014
    20. Wound Healing: A Paradigm for Regeneration Mayo Clinic Proceedings · 2013
    21. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012
    22. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression Journal of Investigative Dermatology · 2009

    Related research 1

    1. Thyroxine (T4) May Promote Re-Epithelialization and Angiogenesis in Wounded Human Skin Ex Vivo PLoS ONE · 2019