Regulatory T Cells Are Required for Normal and Activin-Promoted Wound Repair in Mice

    February 2018 in “ European Journal of Immunology ”
    Eric Haertel, Natasha Joshi, Paul Hiebert … Sabine Werner
    Studysummary In this study, Treg depletion impaired skin wound healing in mice, potentially by altering the cytokine environment and expanding certain T-cell populations, disrupting the normal healing process.
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    Research cited in this study 2

    1. Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding Nature Medicine · 2013
    2. Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair EMBO journal · 1999