Wound Healing: Cellular Mechanisms and Pathological Outcomes

    September 2020 in “ Open Biology ”
    Holly N. Wilkinson, Matthew J. Hardman
    Studysummary This review explores the cellular mechanisms of tissue repair and discusses how advancements in understanding wound pathology could lead to the development of more effective therapies for chronic, non-healing wounds, which are prevalent among individuals with diabetes and aging.
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    Research cited in this study 10

    1. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
    2. The Role Of Estrogen In Cutaneous Aging And Repair Maturitas · 2017
    3. Toll-Like Receptor Function in Acute Wounds Advances in wound care · 2017
    4. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    5. Genetically Induced Cell Death in Bulge Stem Cells Reveals Their Redundancy for Hair and Epidermal Regeneration Stem Cells · 2014
    6. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    7. Skin And Hair On-A-Chip: In Vitro Skin Models Versus Ex Vivo Tissue Maintenance With Dynamic Perfusion Lab on a Chip · 2013
    8. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    9. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    10. Deregulated Expression of c-Myc Depletes Epidermal Stem Cells Nature Genetics · 2001

    Related research 1

    1. Wound Healing: Cellular Mechanisms and Pathological Outcomes Open Biology · 2020